Search on: DIRECT ANTITHROMBINS 
Descriptors Found: 1
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Descriptor English:   Antithrombins 
Descriptor Spanish:   Antitrombinas 
Descriptor Portuguese:   Antitrombinas 
Synonyms English:   Direct Thrombin Inhibitors
Antithrombins, Direct
Thrombin Inhibitors, Direct
Direct Antithrombins  
Tree Number:   D27.505.519.389.745.800.449
D27.505.954.502.119.500
Definition English:   Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins. 
Indexing Annotation English:   ANTITHROMBIN PROTEINS is also available
History Note English:   2011(1964) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   27917 
Unique Identifier:   D000991 

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